inflammatory bowel disease (ibd) is a chronic disease of unknown etiology, in which genetic factors, seem to play an important role in the disease predisposition and course. assessment of tumor necrosis factor (tnf-α) gene polymorphisms in many populations showed a possible association with ibd. considering the genetic variety in different ethnic groups, the aim of the present study was to inve...

Background: The double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. In addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. Materials and Methods: An Iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulpl...

background: the double heterozygous state of α/β thalassemia may alter the hematological indices and modify the phonotype. in addion, definite characterizaon of co-inheritance of α- and β-thalassemia heterozygous carriers may change the process of genec counseling. materials and methods: an iranian couple with low hematological indices was analyzed for α-globin gene deleons using mulplex g...

Background: Correlations between bone marrow, heart, kidney, liver, skin and lung transplant rejection or survival with human cytokine gene polymorphisms have been described. There are also reports about the role of cytokines and Tumor Necrosis Factors-Alpha (TNF-α) on corneal transplant in animal models. Further studies are needed to clarify the role of cytokines in corneal allograft rejection...

during 2004-2007, a field survey was conducted in different vineyards to determine the fungal pathogens associated with grapevine decline in different provinces of iran including fars,hamedan,isfahan, and kohgiluyeh and boirahmad. twenty-seven isolates of botryosphaeriaceae were recovered from vines showing decline and dieback symptoms only in fars province. based on morphological and cultural ...

Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...

background: correlations between bone marrow, heart, kidney, liver, skin and lung transplant rejection or survival with human cytokine gene polymorphisms have been described. there are also reports about the role of cytokines and tumor necrosis factors-alpha (tnf-α) on corneal transplant in animal models. further studies are needed to clarify the role of cytokines in corneal allograft rejection...

background: we aimed to determine the incidence of co-inheritance as well as interaction of sickle cell trait (sct) and α thal /β thal mutations in south and south central of iran. method: we employed a pcr and restriction fragment length polymorphism techniques to confirm diagnosis of sickle cell trait. all subjects were screened for any α/β -thalassemia mutations using a gap-polymerase chain ...